| Distance between laser head and skin does not influence skin blood flow values recorded by laser speckle imaging. | |
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MedLine Citation:
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PMID: 21784084 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Laser Speckle contrast imaging (LSCI) allows non-contact, real-time recording of cutaneous blood flow (CBF). Different distances from laser-head to skin (distances(L-S)) can be chosen by the operator to perform these recordings. We aimed to evaluate the impact of different Distances(L-S) on the analysis of rest blood flow and post-occlusive reactive hyperemia (PORH). METHODS: Four distances(L-S) (10, 15, 20, and 30cm) were evaluated in a random order in 11 healthy subjects. We analyzed the concordance between each recording at each distance(L-S). We compared CBF results (absolute values and cutaneous vascular conductance (CBF divided by mean arterial pressure)) obtained for each distance(L-S). The intra-subject coefficients of variation due to distances(L-S) (intra-CV, in%) were also studied. RESULTS: The mean "r" (standard deviation) cross-correlation coefficient was 0.99 (0.00) between each CBF trace issued from different distance(L-S). Both kinds of CBF results, at rest and for PORH peak, show non-significant differences when the distance(L-S) is modified. The intra-CV varies from 5.9% to 8.6% at rest and from 5.6% to 9.1% for the PORH peak. CONCLUSION: Distance(L-S) neither influences SBFR at rest, nor at peak post-occlusive hyperemia in the 10-30cm interval using LSCI. |
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Authors:
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Guillaume Mahé; Firas Haj-Yassin; Pascal Rousseau; Anne Humeau; Sylvain Durand; Georges Leftheriotis; Pierre Abraham |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-14 |
Journal Detail:
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Title: Microvascular research Volume: - ISSN: 1095-9319 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0165035 Medline TA: Microvasc Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier Inc. |
Affiliation:
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Laboratory of Vascular Investigations, University Hospital of Angers, France; Biologie Neurovasculaire Intégrée (BNVI), Unité mixte UMR CNRS 6214/INSERM 771, Faculté de Médecine, Angers, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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