Document Detail

Distal renal tubular acidosis associated with large vestibular aqueduct and sensorineural hearing loss.
MedLine Citation:
PMID:  16076719     Owner:  NLM     Status:  MEDLINE    
CONCLUSIONS: Hearing loss and equilibrium dysfunction have different etiologies in patients with large vestibular aqueduct syndrome. We suggest that all children with distal renal tubular acidosis (dRTA) should be subjected to an equilibrium study and audiological evaluation, as well as to a CT or MRI scan. OBJECTIVE: dRTA has been described in association with sensorineural hearing loss, but there are no reported cases that have been examined in detail using audiological and equilibrium studies. We report here a case of progressive sensorineural hearing loss with a large vestibular aqueduct and dRTA, and the results of audiological and equilibrium studies. MATERIAL AND METHODS: A 31-year-old female presented with hearing loss, tinnitus and vertigo. She had been treated with oral sodium citrate, potassium citrate and potassium chloride supplementation because of dRTA since the age of 1 month. RESULTS: The pure-tone audiogram of the patient was off the scale for the right ear and showed progressive sensorineural hearing loss for the left ear. Ice-water caloric testing showed canal paresis on the left side. Temporal bone CT and inner ear MRI revealed a large vestibular aqueduct and a large endolymphatic sac on both sides.
Yukiko Shinjo; Kimitaka Kaga; Takashi Igarashi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  125     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-08-03     Completed Date:  2005-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  667-70     Citation Subset:  IM    
Department of Otolaryngology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
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MeSH Terms
Acidosis, Renal Tubular / complications*
Audiometry, Pure-Tone
Caloric Tests / methods
Endolymphatic Sac / abnormalities,  radiography
Follow-Up Studies
Hearing Loss, Sensorineural / etiology*
Semicircular Canals / physiopathology
Temporal Bone / radiography
Tinnitus / etiology
Tomography, X-Ray Computed
Vertigo / etiology
Vestibular Aqueduct / abnormalities*,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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