Document Detail


Disseminated plasmacytoma of the thyroid.
MedLine Citation:
PMID:  20229481     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Extramedullary plasmacytomas most commonly occur in the nasal cavity, nasopharynx, paranasal sinuses, and larynx. Thyroid involvement is rare, as fewer than 75 cases have been previously reported in the literature. We report a new case of disseminated plasmacytoma of the thyroid, which occurred in a 68-year-old woman. The diagnosis was made with an incisional biopsy. The patient initially experienced a complete response to radiotherapy (46.8 Gy in 26 fractions), but she developed multiple metastases at distant sites, including the breast, abdominal wall, and buttock despite various chemotherapy regimens. Ultimately, she was placed on palliative radiotherapy. We also briefly review the diagnostic and treatment options for patients with extramedullary plasmacytoma.
Authors:
Brian J Park; Randy J Kalish; Arthur P Vercillo
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Ear, nose, & throat journal     Volume:  89     ISSN:  1942-7522     ISO Abbreviation:  Ear Nose Throat J     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-06-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701817     Medline TA:  Ear Nose Throat J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  137-9     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
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MeSH Terms
Descriptor/Qualifier:
Biopsy
Combined Modality Therapy
Humans
Plasmacytoma / pathology*,  therapy*
Thyroid Neoplasms / pathology*,  therapy*

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