Document Detail

Disseminated neoplasia in blue mussels, Mytilus galloprovincialis, from the Black Sea, Romania.
MedLine Citation:
PMID:  15946706     Owner:  NLM     Status:  MEDLINE    
Disseminated neoplasia, also called leukemia or hemic neoplasia, has been detected in 15 species of marine bivalve mollusks worldwide. The disease is characterized by the presence of single anaplastic cells with enlarged nuclei and sometimes frequent mitosis, in hemolymph vessels and sinuses. The neoplastic cells gradually replace normal hemocytes leading to the increased mortality of animals. The neoplasia reaches epizootic prevalences in blue mussels, Mytilus trossulus, in some areas, whereas prevalences in Mytilus edulis are generally very low. Mytilus galloprovincialis was suggested to be resistant to the disease although very low prevalences were documented from Spain in the Atlantic Ocean and Italy in the Mediterranean Sea. A case of disseminated neoplasia was discovered in M. galloprovincialis from among 200 specimens studied from the coast of the Romanian Black Sea. Histological preparation revealed the presence of large anaplastic cells with lobed nuclei. This observation extends the geographic range of marine bivalve mollusks with disseminated neoplasia to include the Black Sea.
Corina Ciocan; Inke Sunila
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-06-08
Journal Detail:
Title:  Marine pollution bulletin     Volume:  50     ISSN:  0025-326X     ISO Abbreviation:  Mar. Pollut. Bull.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-21     Completed Date:  2006-08-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0260231     Medline TA:  Mar Pollut Bull     Country:  England    
Other Details:
Languages:  eng     Pagination:  1335-9     Citation Subset:  IM    
National Institute for Marine Research and Development, Grigore Antipa, Mamaia Blv. 300, Constanta 8700, Romania.
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MeSH Terms
Cell Proliferation*
Gills / pathology*
Hemocytes / pathology*
Mediterranean Sea
Mytilus / cytology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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