Document Detail


Disseminated intravascular coagulation with renal and liver damage as the predominant manifestations of recurrent relapses in systemic juvenile rheumatoid arthritis.
MedLine Citation:
PMID:  1575579     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Relapses of systemic juvenile rheumatoid arthritis associated with intravascular coagulation are rare. This paper describes a patient who, over a two year period, had two relapses, each accompanied by evidence of liver and renal damage and disseminated intravascular coagulation. The patient was not receiving non-steroidal anti-inflammatory drugs, and all laboratory and clinical manifestations of her disease rapidly resolved after treatment with prednisone. It is therefore believed that the hepatocellular damage, in addition to the disseminated intravascular coagulation, was a direct manifestation of disease activity. A possible pathogenic role for tumour necrosis factor is suggested.
Authors:
D Schwartz; M Averbuch; A Pines; R Kornovsky; Y Levo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  51     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-06-01     Completed Date:  1992-06-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  347-9     Citation Subset:  IM    
Affiliation:
Department of Medicine T, Ichilov Hospital, Tel-Aviv, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Arthritis, Juvenile Rheumatoid / complications*,  physiopathology
Disseminated Intravascular Coagulation / etiology*,  physiopathology
Female
Humans
Kidney / physiopathology
Kidney Diseases / etiology*
Liver / physiopathology
Liver Diseases / etiology*
Liver Function Tests
Recurrence
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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