Document Detail


Disseminated histoplasmosis: abdominal CT findings in 16 patients.
MedLine Citation:
PMID:  1927816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Since the onset of the AIDS epidemic, disseminated Histoplasma capsulatum infection has been reported with much greater frequency in both endemic and nonendemic areas. Abdominal CT scans of 16 patients with disseminated histoplasmosis were reviewed retrospectively to identify radiologic features of this disease. The diagnosis was confirmed by autopsy (three patients), bone marrow biopsy (10 patients), lymph node biopsy (three patients), bronchoscopic biopsy (three patients), liver biopsy (two patients), and/or colonoscopic biopsy (one patient). Fourteen patients had serologic evidence of human immunodeficiency virus infection. Disseminated histoplasmosis was either the only initial manifestation of AIDS (seven patients) or was accompanied simultaneously by cytomegalovirus infection (four patients), or Kaposi sarcoma, Toxoplasma encephalitis, or cryptosporidiosis (one patient each). Abdominal CT findings included hepatomegaly (63%); splenomegaly (38%); diffuse splenic hypottenuation (19%); bilateral adrenal enlargement or hypoattenuating masses (13%); and enlarged lymph nodes with homogeneous soft-tissue density (44%), diffuse or central low density (13%), or both (19%). Histoplasmosis should be included in the differential diagnosis when abdominal CT scans show such nonspecific findings as hepatomegaly, splenomegaly, enlarged soft-tissue-density or hypoattenuating lymph nodes, or adrenal enlargement or masses in an immunodeficient patient. An uncommon but possibly specific CT finding in histoplasmosis is diffuse splenic hypoattenuation.
Authors:
D R Radin
Related Documents :
17011456 - The utility of 18f-fluorodeoxyglucose positron emission tomography for early diagnosis ...
22508616 - Evaluation of flow cytometric assessment of myeloid nuclear differentiation antigen (mn...
22639286 - Undetectable sensitive serum thyroglobulin (<0.1 ng/ml) in 163 patients with follicular...
22212916 - Fibre integrity and diffusivity of the pyramidal tract and motor cortex within and adja...
16400416 - Statistical voxel-wise analysis of ictal spect reveals pattern of abnormal perfusion in...
14738286 - Syntactic language processing: erp lesion data on the role of the basal ganglia.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  157     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1991-11-18     Completed Date:  1991-11-18     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  955-8     Citation Subset:  AIM; IM; X    
Affiliation:
Department of Radiology, University of Southern California School of Medicine, Los Angeles County-USC Medical Center 90033-1084.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acquired Immunodeficiency Syndrome / complications*
Adult
Hepatomegaly / microbiology,  radiography
Histoplasmosis / complications,  radiography*
Humans
Lymph Nodes / radiography
Male
Opportunistic Infections / complications,  radiography*
Radiography, Abdominal*
Splenomegaly / microbiology,  radiography
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The radiologic diagnosis of Barrett esophagus: importance of mucosal surface abnormalities on air-co...
Next Document:  Primary sclerosing cholangitis: value of cholangiography in determining the prognosis.