Document Detail


Disseminated crytococcosis with extensive cutaneous involvement in AIDS.
MedLine Citation:
PMID:  16912448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cutaneous infections is observed in 15% of patients with disseminated cryptococcosis with AIDS. We present here a case of a 34 years old female with AIDS. She presented with multiple skin coloured umbilicated over face, neck, trunk and limbs, which mimicked molluscum contagiosum and kaposi sarcoma. The tissue from cutaneous lesions was collected by excision biopsy and processed by standard mycological methods. Cryptococcus neoformans was isolated and identified. Cerebrospinal fluid (CSF) also yielded the growth of C. neoformans . Cryptococcal antigen was detected with a titre of 1024 by Latex agglutination, is serum and CSF. Her serum was reactive for HIVI and 2 antibodies. The CD4 lymphocytes count was 80/cmm. The HIV viral load was 2,48,084 copies/mL. She was treated with amphotericin B injectable and oral fluconazole. She responded well and lesions regressed.
Authors:
S N Dharmshale; S A Patil; A Gohil; A Chowdhary; C Oberoi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of medical microbiology     Volume:  24     ISSN:  0255-0857     ISO Abbreviation:  Indian J Med Microbiol     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-08-16     Completed Date:  2006-10-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8700903     Medline TA:  Indian J Med Microbiol     Country:  India    
Other Details:
Languages:  eng     Pagination:  228-30     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Grant Medical College and Sir J J Group of Hospital, Mumbai - 400 008, India. sujatadharmshale@rediffmail.com
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / diagnosis,  drug therapy,  microbiology*
Adult
Amphotericin B / administration & dosage,  therapeutic use
Antifungal Agents / administration & dosage,  therapeutic use
Biopsy
Cryptococcosis / diagnosis,  drug therapy,  microbiology*
Cryptococcus neoformans / isolation & purification*
Dermatomycoses / diagnosis,  drug therapy,  microbiology*
Female
Fluconazole / administration & dosage,  therapeutic use
Humans
Male
Chemical
Reg. No./Substance:
0/Antifungal Agents; 1397-89-3/Amphotericin B; 86386-73-4/Fluconazole

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