Document Detail

Disseminated aspergillosis presenting with endophthalmitis. A case report and a review of the literature.
MedLine Citation:
PMID:  6423266     Owner:  NLM     Status:  MEDLINE    
A patient with idiopathic thrombocytosis developed sudden loss of vision in his left eye secondary to endophthalmitis caused by Aspergillus flavus. He subsequently manifested other symptoms and signs of disseminated infection, and eventually died despite prompt initiation of appropriate parenteral antifungal therapy. A period of profound, iatrogenic neutropenia preceded the development of his terminal infection. Previously reported cases of hematogenously acquired Aspergillus endophthalmitis are reviewed, and approaches to diagnosis and management are discussed. The frequency of eye involvement in cases of disseminated aspergillosis is unknown, but it may be greater than appreciated previously.
D D Demicco; R C Reichman; E J Violette; W C Winn
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer     Volume:  53     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-05-14     Completed Date:  1984-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1995-2001     Citation Subset:  AIM; IM    
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MeSH Terms
Aspergillosis / diagnosis*
Aspergillus flavus / growth & development
Brain Abscess / etiology,  radiography*
Endophthalmitis / diagnosis*,  etiology
Middle Aged
Retina / microbiology
Tomography, X-Ray Computed
Vitreous Body / microbiology

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