| Disseminated aspergillosis in two dogs in Israel. | |
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MedLine Citation:
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PMID: 16466447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Aspergillus terreus, normally a soil or plant saprophyte, causes disseminated systemic infection, involving primarily the skeletal and the cardiopulmonary system in humans and dogs.(1, 2) We describe two cases of German shepherd dogs that were referred to Koret School of Veterinary Medicine Teaching Hospital with a history of anorexia and weakness. Case 1 suffered from neurological deficits, paraparesis and lumbar pain whereas case 2 suffered from unilateral uveitis and exophthalmus. Both dogs were treated symptomatically, but deteriorated progressively despite therapy and were therefore euthanised. Necropsy revealed disseminated aspergillosis, and numerous organs had multiple, miliary, white-yellow foci. Microscopically, these were identified as granulomas, containing fungal hyphae. Affected tissue included brain, heart, kidneys, spleen, lymph nodes and bones (case 2). Aspergillus terreus was isolated from different organs and from urine culture. We suggest that disseminated aspergillosis should be considered as a differential diagnosis in German shepherd dogs presenting with ocular disease, neurological deficits, spinal column pain, urinary system disorders, and radiographic evidence of skeletal and/or respiratory pathology. |
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Authors:
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Y Bruchim; D Elad; S Klainbart |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Mycoses Volume: 49 ISSN: 0933-7407 ISO Abbreviation: Mycoses Publication Date: 2006 Mar |
Date Detail:
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Created Date: 2006-02-09 Completed Date: 2006-05-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8805008 Medline TA: Mycoses Country: Germany |
Other Details:
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Languages: eng Pagination: 130-3 Citation Subset: IM |
Affiliation:
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Emergency and Critical Care Medicine, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel. bruchim@agri.huji.ac.il |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anorexia Aspergillosis / complications, pathology, physiopathology, veterinary* Aspergillus / isolation & purification Dog Diseases / microbiology*, pathology, physiopathology Dogs Exophthalmos / veterinary Female Israel Male Muscle Weakness / veterinary Pain / veterinary Paraparesis Urine / microbiology Uveitis / veterinary |
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