Document Detail

Disseminated Bipolaris spicifera in a neonate.
MedLine Citation:
PMID:  11593377     Owner:  NLM     Status:  MEDLINE    
We report a premature infant with disseminated fungal infection identified as Bipolaris spicifera. The infant was born at 23 4/7 weeks' gestation, weighing 780 g. At day of life (DOL) 7 erythematous areas on the back were noticed that progressed to black, necrotic skin lesions. A shave biopsy showed invasive fungal organisms that were identified by culture as B. spicifera. The lesions progressed despite aggressive surgical debridement and antifungal therapy. On autopsy, fungal organisms found throughout the internal organs confirmed disseminated disease with B. spicifera. This organism is now more often recognized as a human pathogen; however, this is the first reported case in a neonate.
M L Moore; G R Collins; B J Hawk; T S Russell
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  21     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-10-10     Completed Date:  2001-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  399-401     Citation Subset:  IM    
Department of Pediatrics, San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, USA.
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MeSH Terms
Dermatomycoses / diagnosis*,  therapy
Fatal Outcome
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / microbiology*,  therapy
Infant, Very Low Birth Weight
Lung / pathology
Mycoses / diagnosis*,  therapy

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