Document Detail

Dissecting cellulitis treated with the long-pulsed Nd:YAG laser.
MedLine Citation:
PMID:  16918566     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Dissecting cellulitis is a chronic inflammatory scalp condition characterized by pustular nodules, sinus tract formation, and resultant cicatricial alopecia. Current treatments are of limited efficacy. OBJECTIVE: This report explored treating dissecting cellulitis with the long-pulsed Nd:YAG laser to determine the capabilities and limitations of this modality with respect to: (1) reducing pus formation; (2) enabling the termination of systemic treatments; (3) investigating the side-effect profile including dyspigmentation and scarring alopecia; and (4) terminating the disease process. METHODS: This observational study followed four patients with long-standing dissecting cellulitis through consecutive treatments with the long-pulsed Nd:YAG laser without epidermal cooling. RESULTS: One year after initiating laser treatment, patients achieved decreased pus formation, a reduced reliance on systemic treatments, and a controlled or terminated disease process without dyspigmentation. Three patients had regrowth of terminal hairs in treatment sites. CONCLUSION: The long-pulsed Nd:YAG laser is effective in attenuating the progression of dissecting cellulitis without appreciable adverse cutaneous side effects. This is a pilot study, and more patients must be treated in other trials to verify these findings.
Brett D Krasner; Fasahat H Hamzavi; George J Murakawa; Iltefat H Hamzavi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  32     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-21     Completed Date:  2006-09-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1039-44     Citation Subset:  IM    
School of Medicine, Department of Dermatology, Wayne State University, Detroit, Michigan, USA.
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MeSH Terms
African Americans
Cellulitis / radiotherapy*
Chronic Disease
Disease Progression
Laser Therapy*
Pilot Projects
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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