Document Detail

Disruption of atherosclerotic neointima seven years after bare metal stent deployment.
MedLine Citation:
PMID:  22878807     Owner:  NLM     Status:  In-Data-Review    
A 58-year-old male with a history of prior myocardial infarction, hypertension, and dyslipidemia was admitted due to deteriorating exertional angina. A bare metal stent (Multilink plus<sup>TM</sup>, GUIDANT Corporation, Santa Clara, CA, USA) had been implanted into the proximal left anterior descending artery because of ST-elevation myocardial infarction 7 years earlier. Optical coherence tomography (OCT) showed a disruption of the atherosclerotic neointima overlying the stent. Intravascular imaging studies and pathological studies have shown that neointima within a bare-metal stent often transform into atherosclerotic tissue during an extended period of time. In the current report, OCT demonstrated that a disruption of the atherosclerotic neointima has the potential to cause the development of unstable clinical features. OCT examinations therefore help to understand the pathogenesis of acute coronary syndrome after stent implantation.
Shigenobu Inami; Masamichi Takano; Kohji Kato; Asuka Yoshida; Syunsuke Nakamura; Koji Murai; Yukichi Tokita; Gen Takagi; Hitoshi Takano; Kuniya Asai; Masahiro Yasutake; Kyoichi Mizuno
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International heart journal     Volume:  53     ISSN:  1349-3299     ISO Abbreviation:  Int Heart J     Publication Date:  2012  
Date Detail:
Created Date:  2012-08-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244240     Medline TA:  Int Heart J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  261-2     Citation Subset:  IM    
Department of Medicine, Division of Cardiology, Hepatology, Geriatrics and Integrated Medicine, Nippon Medical School.
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