Document Detail

Disproportionate intraventricular septal hypertrophy in Nigerians with essential hypertension.
MedLine Citation:
PMID:  7495208     Owner:  NLM     Status:  MEDLINE    
It is not clear how frequently hypertrophic cardiomyopathy coexists with essential hypertension or whether chronic hypertension per se, induces hypertrophic cardiomyopathy (hypertensive hypertrophic cardiomyopathy). Eighty-three Nigerians with essential hypertension alone underwent M-mode and 2 dimensional echocardiographic study. Twenty per cent (17 patients) had disproportionate intraventricular septal hypertrophy (septum: posterior wall ratio > or = 1.4). These subgroup tended to be elderly, with average age of 57.7 years, and were predominantly male (70%). Two patients in this subgroup (2.4% of total) additionally had thickened posterior left ventricles and a hyperdynamic left ventricular systolic function (fractional fibre shortening of > or = 45%). This picture is consistent with "hypertensive hypertrophic cardiomyopathy". Routine echocardiography may permit the early identification and thus a closer scrutiny and follow up of essential hypertensive patients with disproportionate septal thickness. The prognostic implications of this requires long term study.
A A Ajayi; A O Akintomide; R O Babalola; O Akinwusi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  24     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1996-01-11     Completed Date:  1996-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  NIGERIA    
Other Details:
Languages:  eng     Pagination:  93-6     Citation Subset:  IM    
Department of Medicine, Faculty of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
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MeSH Terms
Age Distribution
Cardiomyopathy, Hypertrophic / etiology*,  physiopathology,  ultrasonography
Hypertension / complications*
Middle Aged
Sex Distribution

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