| Disparate hemodynamic and sympathoadrenergic responses to isometric and mental stress in essential hypertension. | |
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MedLine Citation:
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PMID: 2662733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The hemodynamic and sympathoadrenergic responses during isometric handgrip and mental arithmetic tests were compared in 18 patients with mild essential hypertension. Mean blood pressure increased significantly after both maneuvers (27% during isometric stress and 10.7% during mental stress), but the increase was significantly higher during isometric stress (p less than 0.001). Both stressors increased the heart rate (p less than 0.001) and cardiac output (p less than 0.001). However, the total peripheral resistance behaved differently, for it increased during isometric stress (p less than 0.05) and remained unchanged during mental stress. Both stressors increased the epinephrine levels (p less than 0.005), but only isometric stress increased the norepinephrine levels (p less than 0.001). It is concluded that both stressors increase cardiac output by way of an increase in heart rate, but isometric stress also increases total peripheral resistance and thus causes a greater increase in arterial pressure. Isometric stress activates both the adrenergic and noradrenergic systems, thereby accounting for the exaggerated response in arterial pressure, whereas mental stress stimulates the adrenergic system only. |
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Authors:
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E Grossman; S Oren; G E Garavaglia; R Schmieder; F H Messerli |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 64 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1989 Jul |
Date Detail:
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Created Date: 1989-08-03 Completed Date: 1989-08-03 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 42-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine, Ochsner Clinic, New Orleans, Louisiana. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Cardiac Output Dopamine / blood Epinephrine / blood Female Heart Rate Hemodynamics* Humans Hypertension / blood, physiopathology* Isometric Contraction* Male Mental Processes / physiology Middle Aged Muscle Contraction* Norepinephrine / blood Renin / blood Stress, Physiological / blood, physiopathology* Stress, Psychological / blood, physiopathology* Vascular Resistance |
| Chemical | |
Reg. No./Substance:
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51-41-2/Norepinephrine; 51-43-4/Epinephrine; EC 3.4.23.15/Renin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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