| Disorders of sex development: hormonal management in adolescence. | |
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MedLine Citation:
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PMID: 18584414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hormonal treatment represents the principal aspect of clinical management of people with disorders of sex development (DSD) from adolescence onwards. In fact, individuals with DSD may require sex steroid replacement to induce secondary sex characteristics, to optimize bone mass accrual, and to promote physical and social well-being. Testosterone is the main hormone for treatment in males and estrogens in females. The optimal regimens for sex steroid substitutive therapy in subjects with DSD should be better defined in multi-center prospective studies. Bone health remains a crucial aspect in the management of these persons, but few sound data are available to guide clinical practice. |
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Authors:
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Silvano Bertelloni; Eleonora Dati; Giampiero I Baroncelli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Volume: 24 ISSN: 1473-0766 ISO Abbreviation: Gynecol. Endocrinol. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-27 Completed Date: 2008-09-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8807913 Medline TA: Gynecol Endocrinol Country: England |
Other Details:
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Languages: eng Pagination: 339-46 Citation Subset: IM |
Affiliation:
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Adolescent Medicine, 2nd Pediatric Unit, Department of Obstetrics, Gynecology and Pediatrics, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy. s.bertelloni@med.unipi.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Bone and Bones / drug effects, metabolism Estrogens / administration & dosage* Female Hormone Replacement Therapy / methods* Humans Hypogonadism / drug therapy, metabolism Male Sex Differentiation Disorders / drug therapy*, metabolism Testosterone / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Estrogens; 58-22-0/Testosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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