Document Detail

Disorders of the oesophagus and stomach in infants.
MedLine Citation:
PMID:  9448915     Owner:  NLM     Status:  MEDLINE    
Pathological processes and disease entities in the upper gastrointestinal (GI) tract, specifically those of the oesophagus and the stomach in infancy, have received a disproportionately small amount of attention until recently when appreciation of their pathophysiology and concordant importance in terms of symptomatology has been highlighted. This is probably a phenomenon secondary to improved diagnostic yield from the recent technical advances in areas such as infant endoscopy and a shift in opinion regarding the pathophysiological origin of ubiquitous symptoms of infancy such as feeding disorders, colic and irritability. In addition, the apparently complex interactions of various aetiological factors such as pH-independent gastro-oesophageal reflux (GOR), cow's milk protein intolerance (CMPI), Helicobacter pylori gastritis and upper GI motor disorders have in the past 1-2 years become underlined in terms of aetiopathogenesis and have radically changed thinking regarding diagnosis and therapy of infants with apparent upper-GI-associated symptoms. The contribution to comprehension of infant upper GI disorders of inflammatory paradigms and ontogeny of the upper GI tract is also a recent area worthy of mention. The recent advances in all of these areas and their contribution to the understanding, and subsequent diagnosis and therapy, of upper GI symptoms and their explanation by way of aetiopathogenesis will be explored in this chapter.
M Thomson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Baillière's clinical gastroenterology     Volume:  11     ISSN:  0950-3528     ISO Abbreviation:  Baillieres Clin. Gastroenterol.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1998-03-24     Completed Date:  1998-03-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8704786     Medline TA:  Baillieres Clin Gastroenterol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  547-71     Citation Subset:  IM    
University Department of Paediatric Gastroenterology, Royal Free Hospital, Hampstead, London, UK.
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MeSH Terms
Child, Preschool
Colic / etiology
Gastroesophageal Reflux* / etiology,  pathology,  physiopathology,  therapy
Helicobacter pylori
Milk Hypersensitivity / complications
Peptic Ulcer / microbiology
Stomach Diseases* / pathology,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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