Document Detail

Disorders of interstitial cells of Cajal in a neonate with segmental dilatation of the intestine.
MedLine Citation:
PMID:  20620293     Owner:  NLM     Status:  MEDLINE    
Localized myopathy of the muscular layers may be an important factor contributing to segmental dilatation of the intestine (SDI). Only one report has described SDI of the jejunum in a neonate showing no abnormality of the interstitial cells of Cajal (ICC). The present report describes the very rare case of a neonatal girl with segmental dilatation of the distal duodenum and proximal jejunum with irregular arrangements of Auerbach's plexus and ICC and the successful surgical treatment of SDI. We review the literature on this type of relationship between abnormality of ICC and SDI and discuss the clinical features of this complication. Furthermore, the possible neuropathic cause of SDI complicated with disorders of ICC was explored in this report.
Tadao Okada; Fumiaki Sasaki; Shohei Honda; Kazutosi Cho; Yoshihiro Matsuno; Tomoo Itoh; Kanako C Kubota; Satoru Todo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  45     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e11-4     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Department of Pediatric Surgery, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan.
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MeSH Terms
Diagnosis, Differential
Dilatation, Pathologic
Duodenum / innervation*,  physiopathology,  surgery
Follow-Up Studies
Infant, Newborn
Interstitial Cells of Cajal / pathology*
Intestinal Obstruction / congenital*,  diagnosis,  surgery
Jejunal Diseases / congenital*,  diagnosis,  surgery
Jejunum / innervation*,  physiopathology,  surgery
Radiography, Abdominal

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