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Disorders of glucose metabolism: post mortem analyses in forensic cases-part II.
MedLine Citation:
PMID:  20927632     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In continuation to part I, a literature review is presented concerning biochemical problems of forensic post mortem cases of unclear hyperglycaemia or hypoglycaemia. Clinical parameters for this purpose were recently reviewed. Particular attention was paid to the detection of diabetic ketoacidosis, of hyperosmolar coma, insulinoma, insulin-induced or oral diabetic-induced hypoglycaemia. The second part of the review discusses the analytes ketone bodies, synthetic insulins, human insulin, C-peptide, proinsulin and insulin antibodies. Special interest is given to post mortem matrices for those analytes to reference concentrations, stability data, analytic interferences and analytical procedures which should be used in toxicological laboratories willing to detect diabetic metabolism disorders after death.
Authors:
Frank Musshoff; Cornelius Hess; Burkhard Madea
Publication Detail:
Type:  Journal Article     Date:  2010-10-07
Journal Detail:
Title:  International journal of legal medicine     Volume:  125     ISSN:  1437-1596     ISO Abbreviation:  Int. J. Legal Med.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9101456     Medline TA:  Int J Legal Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  171-80     Citation Subset:  IM    
Affiliation:
Institute of Forensic Medicine, University of Bonn, Stiftsplatz 12, 53111, Bonn, Germany.
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