Document Detail


Disorders of calcium homeostasis in the fetus and neonate.
MedLine Citation:
PMID:  7041784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The physiological mechanisms involved in the alterations in calcium homeostasis during pregnancy are complex. The fetal acquisition of calcium, for skeletal growth, is obtained by an increase in intestinal calcium absorption in the mother with transplacental calcium transfer to the fetus. The regulation of calcium homeostasis during the transition from the intrauterine to the extrauterine environment is complex and poorly understood. Within the first few hours of life the serum calcium concentrations begins to fall progressively reaching a "trough" value by the second or third day of life and then increases to normal values by the tenth day of life. In some neonates the fall in calcium concentration is sufficient to be associated with either tetany or convulsions. Hypocalcemia is probably the commonest disturbance of calcium homeostasis that occurs in the neonate and can be subdivided into three main groups on the basis of the etiological mechanism involved. Other disorders of calcium homeostasis that may affect the neonate include hypoparathyroidism, either congenital or acquired, pseudohypoparathyroidism, and vitamin D deficiency. Hypercalcemia may occur, but is a relatively rare occurrence in the neonate.
Authors:
M R Wills; D E Bruns; J Savory
Related Documents :
22453974 - Calcium stores in vertebrate photoreceptors.
22323814 - Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger.
20398234 - Calcium-dependent physiological processes in trees.
17500934 - Simulations of intracellular calcium release dynamics in response to a high-intensity, ...
6716284 - Calcium release and sarcoplasmic reticulum membrane potential in frog skeletal muscle f...
16751284 - E22k mutation of rlc that causes familial hypertrophic cardiomyopathy in heterozygous m...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annals of clinical and laboratory science     Volume:  12     ISSN:  0091-7370     ISO Abbreviation:  Ann. Clin. Lab. Sci.     Publication Date:    1982 Mar-Apr
Date Detail:
Created Date:  1982-06-21     Completed Date:  1982-06-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0410247     Medline TA:  Ann Clin Lab Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  79-88     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Calcium / analysis
Female
Fetal Diseases / etiology*
Homeostasis
Humans
Hypercalcemia / etiology*
Hyperparathyroidism / complications,  congenital
Hypocalcemia / etiology*
Hypoparathyroidism / congenital,  etiology,  genetics
Hypophosphatasia / diagnosis
Infant
Infant, Newborn
Infant, Newborn, Diseases / etiology*
Magnesium Deficiency / complications
Maternal-Fetal Exchange
Milk / analysis
Pregnancy
Pregnancy Complications / blood
Pseudohypoparathyroidism / physiopathology
Tetany / congenital,  etiology
Vitamin D Deficiency / complications
Chemical
Reg. No./Substance:
7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Improved immunodiagnosis of neutrophil dysfunction in the newborn and infant.
Next Document:  Role of the microtubules in the organization of the Golgi complex (author's transl)