Document Detail


Disopyramide-induced ventricular tachycardia.
MedLine Citation:
PMID:  6153888     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient with ischemic cardiomyopathy and congestive heart failure was treated with disopyramide phosphate for ventricular arrhythmias. The development of ventricular tachycardia was associated with elevated plasma disopyramide levels and prolongation of the QRS and QT intervals, suggesting a disopyramide-induced depression of ventricular conduction and a prolongation of recovery. Thus, in patients with congestive heart failure, as well as in patients with renal and/or hepatic dysfunction, special care must be exercised with respect to the use of disopyramide.
Authors:
K S Lo; K B Gantz; P L Stetson; B R Lucchesi; B Pitt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  140     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1980 Mar 
Date Detail:
Created Date:  1980-05-30     Completed Date:  1980-05-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  413-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Alcoholism / complications
Cardiac Complexes, Premature / drug therapy
Cardiomyopathies / complications
Coronary Disease / complications
Disopyramide / adverse effects*,  blood,  therapeutic use
Heart Failure / blood,  complications
Heart Ventricles
Humans
Male
Middle Aged
Pyridines / adverse effects*
Tachycardia / blood,  chemically induced*
Chemical
Reg. No./Substance:
0/Pyridines; 3737-09-5/Disopyramide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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