Document Detail


Diseases produced by feline caliciviruses when administered to cats by aerosol or intranasal instillation.
MedLine Citation:
PMID:  433113     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Specific pathogen free cats were infected by two feline calicivirus isolates of different plaque type, an extra-large plaque (ep) former and a minute plaque (mp) former. A comparison was made of the disease produced when these isolates were administered by either aerosol or direct intranasal instillation. With both isolates, aerosol infection produced lesions and gave rise to virus replication throughout the respiratory tract. The effects of intranasal infection were more confined to the upper respiratory tract and oropharynx. By both routes of infection the disease produced by the mp virus was clinically and pathologically less severe than that produced by the ep virus.
Authors:
E Ormerod; I A McCandlish; O Jarrett
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  104     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1979 Jan 
Date Detail:
Created Date:  1979-06-11     Completed Date:  1979-06-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Intranasal
Aerosols
Animals
Caliciviridae* / growth & development
Cat Diseases / etiology*,  pathology
Cats
Female
Fever / etiology,  veterinary
Lung / pathology
Male
Pneumonia, Viral / etiology,  pathology,  veterinary
Respiratory Tract Infections / etiology,  pathology,  veterinary*
Virus Diseases / etiology,  pathology,  veterinary*
Chemical
Reg. No./Substance:
0/Aerosols

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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