Document Detail

Diseases associated with chronic rhinosinusitis: what is the significance?
MedLine Citation:
PMID:  18475077     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: To discuss the systemic conditions that may impact the incidence, severity, prognosis, or treatment approach in patients with chronic rhinosinusitis. RECENT FINDINGS: Patients with allergic rhinitis do not necessarily have more severe chronic rhinosinusitis as assessed by symptom scores, nasal endoscopy, or computed tomography staging. However, at least in pediatric patients with chronic rhinosinusitis who undergo surgery, consideration of allergy and allergy treatment appears to improve surgical results. Patients with aspirin sensitivity have a more severe disease, but benefit from surgical treatment to the same degree as non-aspirin-sensitive patients with chronic rhinosinusitis. Surgical treatment of polypoid rhinosinusitis in cystic fibrosis patients improves symptoms, and aggressive surgical opening of sinus cavities may provide long-lasting benefit, though polyps will regrow in most patients, and many will require repeat surgery. Rhinosinusitis is among the most common infectious complications of humoral immunodeficiency, and humoral immunodeficiency is not uncommon in patients with refractory chronic rhinosinusitis. Patients with granulomatous disease causing rhinosinusitis, such as Wegener's granulomatosis, appear to suffer from a symptom burden that is equivalent to the broader population of chronic rhinosinusitis patients. SUMMARY: Systemic disease conditions influence the incidence, treatment, and severity of chronic rhinosinusitis. Specific diagnosis of these contributing conditions will facilitate appropriate treatment.
Matthew W Ryan
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in otolaryngology & head and neck surgery     Volume:  16     ISSN:  1531-6998     ISO Abbreviation:  Curr Opin Otolaryngol Head Neck Surg     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-13     Completed Date:  2008-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9417024     Medline TA:  Curr Opin Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  231-6     Citation Subset:  IM    
Department of Otolaryngology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9035, USA.
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MeSH Terms
Aspirin / adverse effects
Chronic Disease
Cystic Fibrosis / complications
Hypersensitivity / complications
Immunocompromised Host
Rhinitis / etiology*,  therapy
Risk Factors
Severity of Illness Index
Sinusitis / etiology*,  therapy
Vasculitis / complications
Reg. No./Substance:

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