| Disease concomitance in psoriasis. | |
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MedLine Citation:
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PMID: 7751469 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Psoriasis is a multifactorial disease of unknown origin. OBJECTIVE: Our purpose was to determine the frequency of skin disorders concomitantly seen in patients with psoriasis. METHODS: We analyzed data from more than 40,000 patients and calculated sex- and age-adjusted ratios of expected and observed incidence rates of associated disorders. RESULTS: The results demonstrate that, compared with age-matched control patients without psoriasis, cutaneous immune disorders such as allergic contact dermatitis, atopic dermatitis, and urticaria are underrepresented in patients with psoriasis. In contrast, certain systemic disorders such as diabetes, heart insufficiency, and obesity occur significantly more often in patients with psoriasis than in control subjects. Increased resistance to cutaneous bacterial infections was noted only in patients with early-onset psoriasis. CONCLUSION: Our observations show that a distinct pattern of associated diseases exists in patients with psoriasis. Although systemic disorders such as obesity, diabetes, and heart disease may be related to dietary habits and nutritional status, the relative resistance to cutaneous infections together with decreased immune responsiveness suggest a genetically determined selection. |
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Authors:
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T Henseler; E Christophers |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 32 ISSN: 0190-9622 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-06-20 Completed Date: 1995-06-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 982-6 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University of Kiel, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Male Middle Aged Psoriasis / complications* Skin Diseases / complications |
| Comments/Corrections | |
Comment In:
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J Am Acad Dermatol. 1996 Nov;35(5 Pt 1):790-1
[PMID:
8912588
]
J Am Acad Dermatol. 1997 Feb;36(2 Pt 1):281-2 [PMID: 9039193 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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