| Behçet Disease-associated Uveitis Successfully Treated with Golimumab. | |
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MedLine Citation:
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PMID: 23252659 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Over the past decade, the off-label use of biologic agents such as TNF-α antagonists, including infliximab and adalimumab, has improved the treatment armamentarium for refractory immune-mediated uveitis, with particular success in Behçet disease-associated uveitis. Golimumab is a novel fully human anti-TNF-α monoclonal antibody that has been approved for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, with very promising results. Herein, the authors present the use of GLM in a case of Behçet uveitis refractory to other TNF-α blockers. There are only two reports in the literature about the use of GLM in uveitis, describing four patients with JIA-associated uveitis and a case of idiopathic retinal vasculitis. To the authors' knowledge, this is the first report about the use of GLM in Behçet uveitis. |
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Authors:
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Marina Mesquida; María Victoria Hernández; Victor Llorenç; Laura Pelegrín; Gerard Espinosa; Andrew D Dick; Alfredo Adán |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-19 |
Journal Detail:
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Title: Ocular immunology and inflammation Volume: - ISSN: 1744-5078 ISO Abbreviation: Ocul. Immunol. Inflamm. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9312169 Medline TA: Ocul Immunol Inflamm Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Ophthalmology Department, Hospital Clinic of Barcelona, University of Barcelona , Barcelona , Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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