| Discriminant function using red cell indices to distinguish between HbC and HbE traits. | |
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MedLine Citation:
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PMID: 7621626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Values for MCV, MCH, MCHC and red cell distribution width (RDW) derived from subjects with HbC and HbE traits using a Technicon H*1 automated blood count analyser were compared. Significantly higher MCH, MCHC and RDW values were found in those with HbC trait. By use of a simple discriminant function (MCHC2 x RDW/1000), 19/20 subjects with HbC trait gave a value > or = 16.3, and 20/21 subjects with HbE trait gave a value < or = 16.2. The function described may be of value as an adjunct to electrophoresis in intralaboratory quality control. |
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Authors:
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R F Hinchliffe; S P Ellis; J S Lilleyman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical and laboratory haematology Volume: 17 ISSN: 0141-9854 ISO Abbreviation: Clin Lab Haematol Publication Date: 1995 Mar |
Date Detail:
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Created Date: 1995-08-31 Completed Date: 1995-08-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7907061 Medline TA: Clin Lab Haematol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 31-3 Citation Subset: IM |
Affiliation:
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Section of Paediatric Haematology, University of Sheffield Department of Paediatrics, Children's Hospital, Western Bank, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Cell Count Child Child, Preschool Diagnosis, Differential Discriminant Analysis Erythrocyte Indices* Female Hemoglobin C / analysis*, genetics Hemoglobin E / analysis*, genetics Hemoglobinuria / blood, diagnosis*, genetics Humans Infant Male |
| Chemical | |
Reg. No./Substance:
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9008-00-8/Hemoglobin C; 9034-61-1/Hemoglobin E |
| Comments/Corrections | |
Comment In:
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Clin Lab Haematol. 1996 Jun;18(2):128-9
[PMID:
8866152
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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