Document Detail

Discrete subaortic stenosis.
MedLine Citation:
PMID:  6457617     Owner:  NLM     Status:  MEDLINE    
Data concerning 17 consecutive patients with discrete subaortic stenosis are recorded. Twelve patients underwent operative resection of the obstructing lesion. Of these all except one were symptomatic and all had electrocardiographic evidence of left ventricular hypertrophy or left ventricular hypertrophy with strain. They had a peak resting systolic left ventricular outflow tract gradient of greater than 50 mmHg as predicted from the combined cuff measurement of systolic blood pressure and the echocardiographically estimated left ventricular systolic pressure and/or as determined by cardiac catheterisation. The outflow tract gradient as predicted from M-mode echocardiography and peak systolic pressure showed close correlation with that measured at cardiac catheterisation or operation. During the postoperative follow-up from one month to 11 years, of 11 patients, one patient required a further operation for recurrence of the obstruction four years after the initial operation. All patients are now asymptomatic. Five patients have not had an operation. The left ventricular outflow tract gradient as assessed at the time of cardiac catheterisation was greater than 50 mmHg. One patient has been lost to follow-up. The remaining four have been followed from four to eight years and have remained asymptomatic and the electrocardiograms have remained unchanged. Careful follow-up of all patients is essential with continuing clinical assessment, electrocardiograms, M-mode and two-dimensional echocardiograms, and if necessary cardiac catheterisation. Prophylaxis against bacterial endocarditis is also essential.
M M Khan; M P Varma; J Cleland; H O O'Kane; S W Webb; H C Mulholland; A A Adgey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  46     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1982-01-09     Completed Date:  1982-01-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  421-31     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Stenosis, Subvalvular / complications,  physiopathology*,  surgery
Cardiomegaly / etiology
Cardiomyopathy, Hypertrophic / physiopathology*
Follow-Up Studies
Heart / physiopathology

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