Document Detail


Discrepancies between catheter and Doppler estimates of aortic stenosis: the role of pressure recovery evaluated 'in vivo'.
MedLine Citation:
PMID:  17578039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
METHODS: Between 1st January 2000 and 31st March 2005, a total of 259 patients with an aortic valve area (AVA) < or =2 cm(2) was prospectively collected. During a standard diagnostic catheterization, the aortic valve gradient was taken as: [peak left ventricular pressure-- peak aortic pressure]. The AVA was calculated using the Gorlin formula (AG). Echocardiography was performed within 30 days of this procedure. Transvalvular gradients were measured using the Doppler technique, and the AVA was computed using the continuity equation (ACE). The diameter of the ascending aorta was monitored in the parasternal long-axis view, and the values averaged. The ascending aorta sectional area (AA) was then computed according to geometric formulae. In order to correct for pressure recovery, an energy loss coefficient (ELCO) equation was used [ELCO = (AA x ACE)/(AA -ACE)]. Correlations between AG, ACE and ELCO were evaluated by linear regression analysis. As cardiac output affects the estimates of valve areas, the correlation was calculated separately for patients with a median cardiac index (CI) above and below 2.7 1/min/m(2).
RESULTS: A good linear correlation was found between AG and ACE with regression coefficient 0.88, independent of cardiac output. A similar correlation was present between AG and ELCO, with correlation coefficient 0.99 in patients with CI >2.7 1/min/m(2), and
Authors:
Renato Razzolini; Anna Manica; Giuseppe Tarantini; Angelo Ramondo; Massimo Napodano; Sabino Iliceto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  16     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-06-20     Completed Date:  2007-07-19     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  225-9     Citation Subset:  IM    
Affiliation:
Department of Heart, Lung and Vessels, University of Padova, Padova, Italy. renato.razzolini@unipd.it
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MeSH Terms
Descriptor/Qualifier:
Aged
Aortic Valve / physiopathology,  ultrasonography
Aortic Valve Stenosis / physiopathology*,  ultrasonography
Blood Pressure / physiology*
Cardiac Catheterization*
Echocardiography, Doppler*
Female
Humans
Linear Models
Male
Models, Cardiovascular
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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