| Discrepancies between arterial oxygen saturation and functional oxygen saturation measured with pulse oximetry in very preterm infants. | |
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MedLine Citation:
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PMID: 21791935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Discrepancies between pulse oximetry saturation (SpO(2)) and arterial saturation (SaO(2)) at low blood oxygenation values have been previously reported with significant variations among instruments and studies. Whether pulse oximeters that attenuate motion artifact are less prone to such discrepancies is not well known. OBJECTIVE: To prospectively assess the agreement of the Masimo V4 pulse oximeter within the critical 85-95% SpO(2) target range. PATIENTS AND METHODS: For all consecutive babies with gestational age <33 weeks, postnatal age <7 days, and an umbilical arterial line, SpO(2) was measured continuously and SaO(2) analyzed on an as-needed basis. Bland-Altman techniques provided estimates of the difference (D = SaO(2) - SpO(2)), standard deviation (SD), and 95% limits of agreement (D ± 2*SD). RESULTS: There were 1,032 measurements (114 babies) with SpO(2) between 85 and 95%. The 95% limits of agreement were -2.0 ± 5.8, -2.4 ± 9.2, and -1.9 ± 5.3 in the SpO(2) categories 85-95, 85-89, and 91-95%, respectively. For the SpO(2) categories 85-89% and 91-95%, only 52% (53/101) and 59% (523/886) of SpO(2) values, respectively, corresponded to the analogous SaO(2) categories. In the 85-89% SpO(2) category, SaO(2) was lower than 85% in 39 of the 101 (39%) measurements. CONCLUSION: SaO(2) was lower on average than SpO(2) with an increased bias at lower saturation. The -2.4 ± 9.2 95% limits of agreement for SaO(2) - SpO(2) in the 85-89% SpO(2) category suggest that SpO(2) and SaO(2) are not interchangeable and intermittent SaO(2) assessments are warranted when the targeted SpO(2) is within this range. |
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Authors:
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Rhonda J Rosychuk; Ann Hudson-Mason; Dianne Eklund; Thierry Lacaze-Masmonteil |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2011-07-26 |
Journal Detail:
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Title: Neonatology Volume: 101 ISSN: 1661-7819 ISO Abbreviation: Neonatology Publication Date: 2012 |
Date Detail:
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Created Date: 2011-12-22 Completed Date: 2012-07-19 Revised Date: 2012-10-15 |
Medline Journal Info:
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Nlm Unique ID: 101286577 Medline TA: Neonatology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 14-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 S. Karger AG, Basel. |
Affiliation:
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Department of Paediatrics, Stollery's Children Hospital, University of Alberta, Edmonton, Alberta, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Birth Weight Blood Gas Analysis Female Gestational Age Humans Infant, Newborn Infant, Very Low Birth Weight / blood*, physiology Male Oximetry / methods* Oxygen / blood* Prospective Studies Reproducibility of Results Umbilical Arteries / physiology |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
| Comments/Corrections | |
Comment In:
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Neonatology. 2012;101(4):239-40; author reply 240
[PMID:
22156712
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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