| Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries. | |
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MedLine Citation:
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PMID: 22237952 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Dehydrocholic acid was identified as a selective streptavidin binder from a PNA-tagged library. Isothermal calorimetry titration measurements showed this interaction to be entropically driven. Peptides tagged with dehydrocholic acid can be captured on a streptavidin resin and released under thermal conditions. |
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Authors:
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Jean-Pierre Daguer; Mihai Ciobanu; Sofia Barluenga; Nicolas Winssinger |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-12 |
Journal Detail:
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Title: Organic & biomolecular chemistry Volume: - ISSN: 1477-0539 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institut de Science et Ingenierie Supramoleculaires (ISIS), Université de Strasbourg-CNRS (UMR 7006), 8 allee Gaspard Monge, 67000, Strasbourg, France. winssinger@isis.u-strasbg.fr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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