| Discovering pluripotency: 30 years of mouse embryonic stem cells. | |
| | |
MedLine Citation:
|
PMID: 21941277 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Embryonic stem (ES) cells are pluripotent cells isolated from an early embryo and grown as a cell line in tissue culture. Their discovery came from the conjunction of studies in human pathology, mouse genetics, early mouse embryo development, cell surface immunology and tissue culture. ES cells provided a crucial tool for manipulating mouse embryos to study mouse genetics, development and physiology. They have not only revolutionized experimental mammalian genetics but, with the advent of equivalent human ES cells, have now opened new vistas for regenerative medicine. |
| | |
Authors:
|
Martin Evans |
Related Documents
:
|
20937267 - Cryosolvent interaction with cellular actin using 3t3-li cells as a model system. 19516967 - Immunolocalization of non-symbiotic hemoglobins during somatic embryogenesis in chicory. 1597397 - A comparison of critical osmolality and hydraulic conductivity and its activation energ... 19866767 - Erythropoiesis during amphibian metamorphosis : iii. immunochemical detection of tadpol... 18295717 - Transient cell proliferation with polyethylenimine-cationized n-terminal domain of simi... 11221847 - Induction and intracellular regulation of tumor necrosis factor-related apoptosis-induc... |
Publication Detail:
|
Type: Journal Article Date: 2011-09-23 |
Journal Detail:
|
Title: Nature reviews. Molecular cell biology Volume: 12 ISSN: 1471-0080 ISO Abbreviation: Nat. Rev. Mol. Cell Biol. Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-09-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100962782 Medline TA: Nat Rev Mol Cell Biol Country: England |
Other Details:
|
Languages: eng Pagination: 680-6 Citation Subset: IM |
Affiliation:
|
Cardiff University, Museum Avenue, Cardiff, CF10 3AT, Wales, CF10 3XQ, UK. evansmj@cf.ac.uk. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A decade of molecular cell biology: achievements and challenges.
Next Document: Perineural invasion and associated pain in pancreatic cancer.