Document Detail

Discordant and nondiscordant twins: comparative multimethod risk assessment in the neonatal period.
MedLine Citation:
PMID:  11332779     Owner:  NLM     Status:  MEDLINE    
Full-term neonate twins from weight-discordant pairs were compared with nondiscordant pairs on perinatal variables, minor physical anomalies, developmental status, and temperament/interactive measures. For perinatal variables, twins from the top quartile of discordance were found to be at higher risk than other twins. Both the total group of discordant twins and twins with the most extreme discordance had higher weighted minor physical anomaly scores, more minor physical anomalies, and lower developmental status scores than nondiscordant twins. For temperament, twins in the extreme discordant group were more active while awake than twins in the nondiscordant group. The results are discussed in relation to expected group differences in perinatal measures, the timing during gestation of insults related to discordance and minor physical anomalies, and the significance of behavioral differences between cotwins versus between groups. Implications for developmental risk for both twins from discordant pairs are discussed.
M L Riese
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of developmental and behavioral pediatrics : JDBP     Volume:  22     ISSN:  0196-206X     ISO Abbreviation:  J Dev Behav Pediatr     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-05-02     Completed Date:  2001-08-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006933     Medline TA:  J Dev Behav Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  102-12     Citation Subset:  IM    
Louisville Twin Study, Department of Pediatrics, Health Sciences Center, University of Louisville, Kentucky 40292, USA.
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MeSH Terms
Birth Weight*
Congenital Abnormalities / diagnosis,  genetics
Developmental Disabilities / diagnosis,  genetics
Diseases in Twins / genetics*
Infant, Newborn
Neonatal Screening*
Neurologic Examination
Risk Factors
Grant Support

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