Document Detail

Discordant findings between krypton-81m gas and Tc-99m labeled ultrafine aerosol lung ventilation SPECT in two patients with idiopathic pulmonary fibrosis.
MedLine Citation:
PMID:  7788987     Owner:  NLM     Status:  MEDLINE    
Technegas, a newly developed ultra-fine dry dispersion of Tc-99m labeled carbon with a particle size of approximately 5 nm to 20 nm, possesses the properties for lung ventilation imaging using SPECT. The authors observed a discrepancy between krypton-81m gas and technegas lung ventilation SPECT in two patients with idiopathic pulmonary fibrosis who demonstrated heterogeneously decreased distribution of technegas without regions of high count density (focal hot spots) of tracer in their lungs in spite of the almost homogenous distribution of krypton-81m gas. This finding could be explained by the duration of radioactive gas inhalation. Technegas lung ventilation SPECT images reflected lung ventilation with tidal breathing. Conversely, Kr-81m gas lung ventilation SPECT images reflected not only lung ventilation, but also lung volumes. These two radioactive agents for lung ventilation SPECT show different findings.
N Watanabe; T Inoue; S Tomioka; T Yamaji; K Endo
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  20     ISSN:  0363-9762     ISO Abbreviation:  Clin Nucl Med     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-07-25     Completed Date:  1995-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  315-7     Citation Subset:  IM    
Department of Nuclear Medicine, School of Medicine, Gunma University, Japan.
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MeSH Terms
Administration, Inhalation
Krypton Radioisotopes / diagnostic use*
Lung / radionuclide imaging*
Middle Aged
Pulmonary Fibrosis / radionuclide imaging*
Sodium Pertechnetate Tc 99m / diagnostic use*
Tomography, Emission-Computed, Single-Photon*
Reg. No./Substance:
0/Krypton Radioisotopes; 112263-77-1/Technegas; 23288-60-0/Sodium Pertechnetate Tc 99m

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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