Document Detail

Discordant Presentation of Biliary Atresia In Premature Monozygotic Twins.
MedLine Citation:
PMID:  22847464     Owner:  NLM     Status:  Publisher    
ABSTRACT: Biliary atresia is a rare disease of infancy with a relatively unknown etiology. We report a case of premature, 27-week monozygotic twins who are discordant for the development of biliary atresia. We systematically reviewed the literature, and found 30 cases of twins with biliary atresia; only two sets were concordant for the disease. The case was complicated by a delay in diagnosis related to the prematurity of the patient and a comparison to the twin's clinical course. This case supports the theory that the etiology of biliary atresia is related to epigenetic modification.
Sara C Fallon; Shirong Chang; Milton J Finegold; Saul J Karpen; Mary L Brandt
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-26
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  -     ISSN:  1536-4801     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
*Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX †Department of Pathology and Immunology, Texas Children's Hospital, Houston, TX ‡Department of Pediatrics/Liver Center, Emory, Atlanta, Georgia.
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