Document Detail


Discordance of signs in monozygotic twins concordant for the Goldenhar anomaly.
MedLine Citation:
PMID:  3400721     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concordance for Goldenhar anomaly has been described in monozygotic (MZ) twins on 2 occasions but never in dizygotic (DZ) twins. In both cases the twins were similarly, although not identically, affected. We report on a pair of probably monozygotic twins (8% probability of DZ) who presented with extremely diverse manifestations of this anomaly complex. One of them required a tracheostomy because of obstructive apnea due to severe micrognathia and subsequently died. This twin had a midline lower lip cleft which has not previously been described in the Goldenhar anomaly.
Authors:
C A Ryan; N N Finer; E Ives
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  29     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-08-31     Completed Date:  1988-08-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  755-61     Citation Subset:  IM    
Affiliation:
Department of Newborn Medicine, Royal Alexandra General Hospital, Edmonton, Alberta, Canada.
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MeSH Terms
Descriptor/Qualifier:
Diseases in Twins*
Female
Goldenhar Syndrome / genetics*
Humans
Infant, Newborn
Mandibulofacial Dysostosis / genetics*
Maxillofacial Development
Twins*
Twins, Monozygotic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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