Document Detail


Disc replacement using Pro-Disc C versus fusion: a prospective randomised and controlled radiographic and clinical study.
MedLine Citation:
PMID:  17106665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Anterior cervical discectomy and fusion (ACDF) may be considered to be the gold standard for treatment of symptomatic degenerative disc disease within the cervical spine. However, fusion of the segment may result in progressive degeneration of the adjacent segments. Therefore, dynamic stabilization procedures have been introduced. Among these, artificial disc replacement by disc prosthesis seems to be promising. However, to be so, segmental motion must be preserved. This, again, is very difficult to judge and has not yet been proven. The aim of the current study was to first analyse the segmental motion following artificial disc replacement using a disc prosthesis. A second aim was to compare both segmental motion as well as clinical result to the current gold standard (ACDF). This is a prospective controlled study. Twenty-five patients with cervical disc herniation were enrolled and assigned to either study group (receiving a disc prosthesis) or control group (receiving ACDF, using a cage with bone graft and an anterior plate.) Radiostereometric analysis was used to quantify intervertebral motion immediately as well as 3, 6, 12 and 24 weeks postoperatively. Further, clinical results were judged using visual analogue scale and neuro-examination. Cervical spine segmental motion decreased over time in the presence of disc prosthesis or ACDF. However, the loss of segmental motion is significantly higher in the ACDF group, when looked at 3, 6, 12 and 24 weeks after surgery. We observed significant pain reduction in neck and arm postoperatively, without significant difference between both groups (P > 0.05). Cervical spine disc prosthesis preserves cervical spine segmental motion within the first 6 months after surgery. The clinical results are the same when compared to the early results following ACDF.
Authors:
A Nabhan; F Ahlhelm; T Pitzen; W I Steudel; J Jung; K Shariat; O Steimer; F Bachelier; D Pape
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2006-11-14
Journal Detail:
Title:  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society     Volume:  16     ISSN:  0940-6719     ISO Abbreviation:  Eur Spine J     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-03-19     Completed Date:  2007-06-05     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  9301980     Medline TA:  Eur Spine J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  423-30     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University of Saarland, Homburg, Germany. dr_a_nabhan@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Arthroplasty, Replacement / methods*
Bone Screws
Cervical Vertebrae / physiology,  radiography,  surgery
Diskectomy / methods*
Female
Humans
Intervertebral Disc / radiography*,  surgery*
Intervertebral Disc Displacement / radiography,  surgery*
Male
Middle Aged
Prospective Studies
Prosthesis Implantation / methods
Range of Motion, Articular
Spinal Fusion / methods*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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