Document Detail

Disappearing enhancing brain lesion in a child with neurofibromatosis type I.
MedLine Citation:
PMID:  9126587     Owner:  NLM     Status:  MEDLINE    
Neurofibromatosis type 1 (NF1) in children can produce a variety of parenchymal signal abnormalities on cranial MR. Areas of abnormal signal in these patients may represent regions of disordered myelination, "hamartomatous" change or frank neoplasia. The presence of contrast enhancement in intracranial lesions in patients with NF1 is usually strongly suggestive of tumor. We report the case of a child with NF1 and a focal enhancing brain parenchymal lesion which spontaneously resolved without specific therapy.
P W Morris; C M Glasier; J G Smirniotopoulos; J W Allison
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric radiology     Volume:  27     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-05-14     Completed Date:  1997-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  260-1     Citation Subset:  IM    
Department of Pediatrics, Arkansas Children's Hospital, Little Rock 72202-3591, USA.
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MeSH Terms
Brain / pathology*
Brain Neoplasms / diagnosis
Magnetic Resonance Imaging
Neurofibromatosis 1 / diagnosis,  pathology*
Remission, Spontaneous

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