Document Detail


Disappearance of a syndrome: Dressler's syndrome in the era of thrombolysis.
MedLine Citation:
PMID:  7987883     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The incidence of the post-myocardial infarction syndrome (Dressler's syndrome) among thrombolized patients has not been established yet. To clarify this issue we prospectively studied 201 consecutive patients with acute myocardial infarction who had undergone recombinant tissue-type plasminogen activator therapy followed by 5 days of heparin administration. All patients were followed for at least 3 months for clinical signs of Dressler's syndrome. None of the 148 patients (76%) who showed clinical signs of early reperfusion had Dressler's syndrome. The sole patient in the group who manifested the syndrome developed it 3 weeks following extensive anterior myocardial infarction with no evidence of reperfusion. Although 4 patients manifested signs of early pericarditis, none developed the syndrome. We conclude that Dressler's syndrome has in fact been rendered a rare phenomenon among patients who benefit from thrombolytic therapy.
Authors:
A Shahar; H Hod; G M Barabash; E Kaplinsky; M Motro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  85     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1994  
Date Detail:
Created Date:  1995-01-10     Completed Date:  1995-01-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  255-8     Citation Subset:  IM    
Affiliation:
Emergency Department and Heart Institute, Sheba Medical Center, Tel-Hashomer, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Fever / etiology
Humans
Male
Middle Aged
Myocardial Infarction / complications*,  drug therapy
Pericardial Effusion / etiology
Pericarditis / etiology*
Pneumonia / etiology
Syndrome
Thrombolytic Therapy*
Tissue Plasminogen Activator / therapeutic use
Chemical
Reg. No./Substance:
EC 3.4.21.68/Tissue Plasminogen Activator
Comments/Corrections
Comment In:
Cardiology. 1995;86(5):444   [PMID:  7585752 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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