Document Detail


Disability and progression in Parkinson's disease.
MedLine Citation:
PMID:  899718     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Disability and progression in Parkinson's disease prior to levodopa treatment was investigated in a random group of 442 patients representing 91 per cent of all known cases with Parkinson's disease in a defined area. Almost half the patients were totally independent, 27 per cent needed help occasionally, and 25 per cent were dependent on other people. Ten per cent of the patients had only unilateral symptoms, 57 per cent had bilateral involvement with mild disability, 20 per cent had a moderately advanced disease, and 13 per cent were severely idsabled. A great variation was found in progression rates. In individual cases, however, the progression rate seemed to be relatively fixed. Concurrent arteriosclerosis was found to worsen the prognosis, whereas the beginning of the disease with tremor and the occurrence of prominent tremor promised a slower progression. Twenty-six patients with only unilateral symptoms 10 years after onset of the disease were found to correspond to postencephalitic patients in age structure, and in such cases a history of preceeding viral infection of the central nervous system was observed on four occasions.
Authors:
R J Marttila; U K Rinne
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  56     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-10-20     Completed Date:  1977-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  159-69     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Disability Evaluation
Female
Finland
Humans
Male
Middle Aged
Parkinson Disease / diagnosis*
Parkinson Disease, Postencephalitic / diagnosis
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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