Document Detail


Directional sensitivity of "first trial" reactions in human balance control.
MedLine Citation:
PMID:  19279150     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Support-surface movements are commonly used to examine balance control. Subjects typically receive a series of identical or randomly interspersed multidirectional balance perturbations and the atypical "first trial reaction" (evoked by the first perturbation) is often excluded from further analysis. However, this procedure may obscure vital information about neurophysiological mechanisms associated with the first perturbation and, by analogy, fully unexpected falls. We studied first trial reactions, aiming to clarify their directional impact on postural control and to characterize the underlying neurophysiological substrate. We instructed 36 subjects to maintain balance following support-surface rotations in six different directions. Perturbations in each direction were delivered in blocks, consisting of 10 serial stimuli. Full body kinematics, surface reactive forces, and electromyographic (EMG) responses were recorded. Regardless of direction, for the very first rotation, displacement of the center of mass was 15% larger compared with the ensuing nine identical rotations (P < 0.0001). This first trial reaction immediately reemerged whenever a new perturbation direction was introduced. First trial reactions (and near-falls) were greatest for backward-directed rotations and smallest for laterally directed rotations. This directional dependence coincided with early changes in vertical head accelerations. First trial reactions in EMG responses involved larger amplitudes in general and earlier muscle response onsets in upper body muscles. These findings show that first trial reactions are associated with significantly increased postural instability, mainly due to increased response amplitudes. Although rapid habituation occurs following presentation of identical stimuli, subjects immediately become unstable again when the perturbation direction suddenly changes. Excessive responses due to a failure to combine proprioceptive and vestibular cues effectively may explain this instability seen with first trials, particularly when falling backward.
Authors:
Lars B Oude Nijhuis; John H J Allum; George F Borm; Flurin Honegger; Sebastiaan Overeem; Bastiaan R Bloem
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-11
Journal Detail:
Title:  Journal of neurophysiology     Volume:  101     ISSN:  0022-3077     ISO Abbreviation:  J. Neurophysiol.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-27     Completed Date:  2009-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375404     Medline TA:  J Neurophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2802-14     Citation Subset:  IM    
Affiliation:
University of Otorhinolaryngology, University Hospital, CH-4031 Basel, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biomechanics
Confidence Intervals
Electromyography / methods
Female
Humans
Knee / innervation
Male
Movement / physiology*
Muscle, Skeletal / innervation
Orientation / physiology*
Postural Balance / physiology*
Proprioception*
Time Factors
Torque
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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