Document Detail


Directional coronary atherectomy: optimal atherectomy trials and new combined strategies with coronary stents.
MedLine Citation:
PMID:  11244516     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Directional coronary atherectomy (DCA) has evolved from its early use as a tool for minimal plaque debulking to its current use of more aggressive lumen enlargement. The trend toward improved lumen results and reduced restenosis following DCA compared to percutaneous transluminal coronary angioplasty (PTCA) in the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT) was confirmed as a significant improvement in the subsequent Balloon versus Optimal Atherectomy Trial (BOAT). BOAT showed that acute lumen results and late angiographic restenosis could be significantly improved by DCA over PTCA, without any increase in procedural complications or late cardiac events. The role of DCA in conjunction with coronary stents is currently being defined as studies suggest that residual plaque burden after stenting is predictive of late restenosis. The Atherectomy before Multilink Stent Improves Lumen Gain and Clinical Outcomes Study (AMIGO) will help determine whether plaque debulking prior to stenting can reduce restenosis.
Authors:
C A Simonton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in interventional cardiology : SIIC     Volume:  5     ISSN:  1084-2764     ISO Abbreviation:  Semin Interv Cardiol     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-03-13     Completed Date:  2001-04-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9606070     Medline TA:  Semin Interv Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  193-8     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Harcourt Publishers Ltd.
Affiliation:
The Sanger Clinic, Charlotte, NC 28203, USA. csimonton@sanger-clinic.com
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MeSH Terms
Descriptor/Qualifier:
Atherectomy, Coronary*
Coronary Angiography
Coronary Artery Disease / surgery*,  therapy
Coronary Vessels / ultrasonography
Humans
Randomized Controlled Trials as Topic
Recurrence / prevention & control
Stents*
Treatment Outcome
Ultrasonography, Interventional

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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