| Direction of motion discrimination after early lesions of striate cortex (V1) of the macaque monkey. | |
| | |
MedLine Citation:
|
PMID: 11134530 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Previous studies have established that humans and monkeys with damage to striate cortex are able to detect and localize bright targets within the resultant scotoma. Electrophysiological evidence in monkeys suggests that residual vision also might include sensitivity to direction of visual motion. We tested whether macaque monkeys with longstanding lesions of striate cortex (V1), sustained in infancy, could discriminate visual stimuli on the basis of direction of motion. Three monkeys with unilateral striate cortex lesions sustained in infancy were tested 2-5 years postlesion on a direction of motion discrimination task. Each monkey was trained to make saccadic eye movements to a field of moving dots or to withhold such eye movements, depending on the direction of motion in a coherent random dot display. With smaller motion displays, monkeys were unable to detect or discriminate motion within the scotoma, although they could discriminate moving from static stimuli. Yet, each monkey was able to discriminate direction of motion when the motion stimulus was larger, but still confined to the scotoma. The results demonstrate that the recovery after infant damage to striate cortex includes some sensitivity to direction of visual motion. |
| | |
Authors:
|
T Moore; H R Rodman; C G Gross |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 98 ISSN: 0027-8424 ISO Abbreviation: Proc. Natl. Acad. Sci. U.S.A. Publication Date: 2001 Jan |
Date Detail:
|
Created Date: 2001-01-26 Completed Date: 2001-04-19 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 7505876 Medline TA: Proc Natl Acad Sci U S A Country: United States |
Other Details:
|
Languages: eng Pagination: 325-30 Citation Subset: IM |
Affiliation:
|
Department of Psychology, Green Hall, Princeton University, Princeton, NJ 08544-1010, USA. tirin@princeton.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aging
/
physiology Animals Behavior, Animal / physiology Brain Injuries / physiopathology* Discrimination (Psychology) / physiology* Female Macaca fascicularis / physiology* Motion* Photic Stimulation Time Factors Visual Cortex / cytology, injuries, physiology, physiopathology* Visual Perception / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
EY-11374/EY/NEI NIH HHS; MH-12336/MH/NIMH NIH HHS; MH-19420/MH/NIMH NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Multiple neural correlates of detection in the human brain.
Next Document: Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase...