Document Detail

Directed modification instead of normalization of fatty acid patterns in cystic fibrosis: an emerging concept.
MedLine Citation:
PMID:  11224654     Owner:  NLM     Status:  MEDLINE    
Fatty acid patterns divergent from controls have been described in patients with cystic fibrosis. The range of this divergence is very broad. In some patients the plasma fatty acid pattern is normal, others only have abnormalities of a few essential fatty acids, some have fatty acid deviations tending to a reduced essential fatty acid status or have overt essential fatty acid deficiency. In the past, several nutritional interventions were aimed at normalizing deviating fatty acid patterns. Over the years, biochemical findings have been reported that suggest that it may be more beneficial to change fatty acid status in a directed way rather than normalizing it.
A Christophe; E Robberecht
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in clinical nutrition and metabolic care     Volume:  4     ISSN:  1363-1950     ISO Abbreviation:  Curr Opin Clin Nutr Metab Care     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-06     Completed Date:  2001-07-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9804399     Medline TA:  Curr Opin Clin Nutr Metab Care     Country:  England    
Other Details:
Languages:  eng     Pagination:  111-3     Citation Subset:  IM    
Department of Endocrinology and Metabolic Diseases, Division of Nutrition, 6K12 Ghent University Hospital, De Pintelaan 185, B 9000 Ghent, Belgium.
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MeSH Terms
Cystic Fibrosis / metabolism*,  physiopathology
Docosahexaenoic Acids / administration & dosage*
Eicosanoids / biosynthesis
Fatty Acids / blood*,  metabolism
Nutritional Status
Reg. No./Substance:
0/Eicosanoids; 0/Fatty Acids; 25167-62-8/Docosahexaenoic Acids

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