Document Detail


Direct thrombin inhibitors and factor Xa inhibitors in patients with cerebrovascular disease.
MedLine Citation:
PMID:  22288673     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Stroke is a leading cause of cardiovascular morbidity and mortality worldwide. Approximately, 795,000 strokes occur in the USA each year, 610,000 of which are first events, and 185,000 of which are recurrent events. Of all strokes, 87% are ischemic strokes. Novel anticoagulants serve as an alternative antithrombotic intervention in patients with ischemic cerebrovascular disease. This paper reviews the role of the novel anticoagulants, dabigatran, rivaroxaban and apixaban, in stroke prevention among patients with nonvalvular atrial fibrillation.
Authors:
Sarkis Morales-Vidal; Michael J Schneck; Murray Flaster; José Biller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of neurotherapeutics     Volume:  12     ISSN:  1744-8360     ISO Abbreviation:  Expert Rev Neurother     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101129944     Medline TA:  Expert Rev Neurother     Country:  England    
Other Details:
Languages:  eng     Pagination:  179-90     Citation Subset:  IM    
Affiliation:
Department of Neurology, Stroke Program, Loyola University Chicago, Stritch School of Medicine, Maywood, IL 60153, USA.
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