Document Detail


Direct monitoring by carbon-13 nuclear magnetic resonance spectroscopy of the metabolism and metabolic rate of 13C-labeled compounds in vivo.
MedLine Citation:
PMID:  2049803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Carbon-13 nuclear magnetic resonance spectroscopy has been used to observe the transformations of [1-13C]-D-glucose to [1,1'-13C2]-D-trehalose, and [3-13C]-L-alanine to [2-13C]-L-glutamic acid in the living body of Gryllodes sigillatus. [3-13C]-D-Alanine was not metabolized. The metabolic rate of [1-13C]-D-glucose was found to be altered by prior injection of boric acid.
Authors:
K Iida; O Hidoh; J Fukami; M Kajiwara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chemical & pharmaceutical bulletin     Volume:  39     ISSN:  0009-2363     ISO Abbreviation:  Chem. Pharm. Bull.     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-07-22     Completed Date:  1991-07-22     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0377775     Medline TA:  Chem Pharm Bull (Tokyo)     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  210-3     Citation Subset:  IM    
Affiliation:
Department of Medicinal Chemistry, Meiji College of Pharmacy, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Alanine / metabolism*
Animals
Carbon Isotopes*
Glucose / metabolism*
Gryllidae / metabolism*
Magnetic Resonance Spectroscopy / methods*
Chemical
Reg. No./Substance:
0/Carbon Isotopes; 50-99-7/Glucose; 56-41-7/Alanine

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