Document Detail

Direct interaction and cooperative role of tumor suppressor p16 with band 3 (AE1).
MedLine Citation:
PMID:  15811326     Owner:  NLM     Status:  MEDLINE    
By using the C-terminal 112-residue of band 3 to screen the K562 cDNA library, we find that the p16 interacts with band 3, which was confirmed both in yeast and in mammalian cells. Functional experiments show that p16 facilitates the movement of band 3 to plasma membrane with increased anion transport activity in 293t cells. Moreover, expression of endogenous p16 in 293t cells was increased at 24 and 36 h after transfection with band 3. Our findings provide a novel regulation pathway for both band 3 and p16.
Guo-Hui Fu; Yong Wang; Yu-Hui Xi; Wei-Wei Shen; Xiao-Yan Pan; Wu-Zhong Shen; Xiao-Shu Jiang; Guo-Qiang Chen
Related Documents :
12080086 - Mammalian cell size is controlled by mtor and its downstream targets s6k1 and 4ebp1/eif4e.
11913456 - Signaling and gene regulation by urea in cells of the mammalian kidney medulla.
11208096 - Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytos...
7579666 - Enhancing expression of recombinant proteins in mammalian cells using the herpesvirus v...
1567676 - Residual dna damage: what is left over and how does this determine cell fate?
6474446 - Electron microscopic comparison of the tunica media of the thoracic aorta between species.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  579     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-06     Completed Date:  2005-05-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2105-10     Citation Subset:  IM    
Department of Pathophysiology, Shanghai Institute of Hematology, Rui-Jin Hospital, Shanghai Second Medical University (SSMU), Shanghai 200025, PR China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acid Sequence
Anion Exchange Protein 1, Erythrocyte / metabolism*
Blotting, Western
Cell Line
Cyclin-Dependent Kinase Inhibitor p16 / metabolism*
Molecular Sequence Data
Protein Binding
Two-Hybrid System Techniques
Reg. No./Substance:
0/Anion Exchange Protein 1, Erythrocyte; 0/Cyclin-Dependent Kinase Inhibitor p16

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  BLG-e1 - a novel regulatory element in the distal region of the beta-lactoglobulin gene promoter.
Next Document:  Acetylcholine from vagal stimulation protects cardiomyocytes against ischemia and hypoxia involving ...