Document Detail


Direct and indirect assessment of skeletal muscle blood flow in patients with congestive heart failure.
MedLine Citation:
PMID:  8938578     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Techniques which are currently used to measure skeletal muscle blood flow (SMBF) in patients with congestive heart failure (CHF) are neither convenient nor accurate. They have led to discrepant results in patients with congestive heart failure and are, in part, responsible for the ongoing debate regarding the factors which limit the rise in body oxygen consumption during exercise in these patients. However, direct measurement of SMBF may not be needed during exercise in patients with severe CHF. Their skeletal muscles maximally extract oxygen. Consequently, increase in oxygen consumption by the skeletal muscles is only mediated by a concomitant increase in SMBF. In patients with severe CHF, peak body oxygen consumption attained during maximal exercise closely depends on the rise in SMBF, and thus provides an indirect measurement of SMBF.
Authors:
T H LeJemtel; M Testa; G Jondeau
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Journal of molecular and cellular cardiology     Volume:  28     ISSN:  0022-2828     ISO Abbreviation:  J. Mol. Cell. Cardiol.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-02-28     Completed Date:  1997-02-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0262322     Medline TA:  J Mol Cell Cardiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2249-54     Citation Subset:  IM; S    
Affiliation:
Division of Cardiology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
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MeSH Terms
Descriptor/Qualifier:
Heart Failure / physiopathology*
Humans
Muscle, Skeletal / blood supply*
Oxygen Consumption
Physical Exertion
Regional Blood Flow

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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