Document Detail

Direct evidence of luteal insufficiency in women with habitual abortion.
MedLine Citation:
PMID:  865734     Owner:  NLM     Status:  MEDLINE    
Plasma levels of progesterone were measured during the luteal phase in 10 of 15 women with clinical histories of at least three spontaneous abortions in the last three gestations, and in 15 healthy nonpregnant women during the same phase of the ovarian cycle. Progesterone values found in the women with habitual abortion were lower (P less than 0.05-0.005) than in the nonpregnant group almost throughout the period of observation. The habitually aborting women who became pregnant again aborted between the seventh and 12th weeks. Their progesterone concentrations were less than 6 ng/ml, 48-72 hours before vaginal bleeding or abortion. These values were compared with those found during the first 12 weeks in normal pregnancy (P less than 0.001). The results suggest a useful method of evaluating the treatment of habitual abortion.
J L Horta; J G Fernández; B S de León; V Cortés-Gallegos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  49     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1977 Jun 
Date Detail:
Created Date:  1977-07-18     Completed Date:  1977-07-18     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  705-8     Citation Subset:  AIM; IM    
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MeSH Terms
Abortion, Habitual / blood,  physiopathology*
Corpus Luteum Maintenance*
Pregnancy Trimester, First
Progesterone / blood*,  physiology
Reg. No./Substance:

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