Document Detail

Direct determination of volume- and time-dependence of alveolar surface tension in excised lungs.
MedLine Citation:
PMID:  277943     Owner:  NLM     Status:  MEDLINE    
We measured alveolar surface tension directly by observing the spreading properties of fluid droplets placed by micropipette within individual alveoli. Alveolar surface tension in excised rat lungs at total lung capacity and 37 degrees was 29.7 +/- 1.4 mN-m-1. In lungs held at functional residual capacity, surface tension changed slowly, rising to 9 mN-m-1 at 30 min with a subsequent approximately linear rise to 16 mN-m-1 at 115 min. Thereafter it rose more rapidly (20 mN-m-1 at 140 min), suggesting that it was not asymptotically approaching an equilibrium value.
S Schürch; J Goerke; J A Clements
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  75     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-10-25     Completed Date:  1978-10-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  3417-21     Citation Subset:  IM    
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MeSH Terms
Functional Residual Capacity
Pulmonary Alveoli / physiology*
Pulmonary Surfactants / physiology
Surface Tension
Total Lung Capacity
Reg. No./Substance:
0/Fluorocarbons; 0/Pulmonary Surfactants; 0/Silicones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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