Document Detail


Direct determination of local oxygen consumption of the brain cortex in vivo.
MedLine Citation:
PMID:  564039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A method is described to determine local oxygen consumption quantitatively in the brain cortex under in vivo conditions. Local oxygen consumption is calculated from the slope of local tissue PO2 decrease during a few seconds of total ischemia of the brain for each second after the stop of circulation. The decrease of tissue PO2 is recorded simultaneously at several measuring sites. To be independent of oxygen chemically bound to hemoglobin, tissue PO2 values are raised above 100 Torr. The calculation of local oxygen consumption for each second during the short period of ischemia showed that the O2 consumption remains constant only for a few seconds ranging from 5 to maximally 15 s at different locations. The O2 consumption decreases continuously although the tissue PO2 values are still above the full saturation of hemoglobin. The rate of local oxygen consumption varies considerably at different measuring sites of the superficial layers of the brain cortex (cat). The mean value amounts to 3 +/- 1.5 ml O2/100 g tissue and minute.
Authors:
E Leniger-Follert
Related Documents :
2896569 - Haematology and metabolism of the blood of the little penguin, eudyptula minor.
613809 - The influence of electrical stimulation on cortex po2 level in the rat brain.
2919679 - Postprandial gastrointestinal blood flow and oxygen consumption during environmental co...
14499489 - Primitive, and protective, our cellular oxygenation status?
1451149 - Metabolic vasodilatation with glucose-insulin-potassium does not change the heterogeneo...
9716299 - Effects of hypoxia, blood p(co2) and flow on o2 transport in excised rabbit lungs.
22579889 - Weaning from venovenous extracorporeal membrane oxygenation without anticoagulation: is...
10174299 - Incidence of electrocardiographic changes during cytapheresis using an intermittent flo...
8922889 - Half-dose aprotinin does not affect haemorheological properties in patients undergoing ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  372     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-03-10     Completed Date:  1978-03-10     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  175-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cats
Cerebral Cortex / physiology*
Electroencephalography
Ischemia / physiopathology
Oxygen Consumption*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The area postrema and control of arterial blood pressure; absence of hypertension after excision of ...
Next Document:  Exercise induced augmentation of myocardial oxygen extraction in spite of normal coronary dilatory c...