| Direct assessment of effective renal plasma flow from renoscintigraphy with a gamma camera and an on-line computer. | |
| | |
MedLine Citation:
|
PMID: 7329809 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A concept of a kidney uptake coefficient (UC) of 131I-o-hippurate was developed by analogy from the corresponding kidney clearance of blood plasma in the early period after injection of the hippurate. The UC for each kidney was defined as the count-rate over its ROI at a time shorter than the peak in the renoscintigraphic curve divided by the integral of the count-rate curve over the "blood"-ROI. A procedure for normalization of both curves against each other was also developed. The total kidney clearance of the hippurate was determined from the function of plasma activity concentration vs. time after a single injection; the determinations were made at 5, 10, 15, 20, 30, 45, 60, 75 and 90 min after intravenous administration of 131I-o-hippurate and the best-fit curve was obtained by means of the least-square method. When the UC was related to the absolute value of the clearance a positive linear correlation was found (r = 0.922, p greater than 0.99). Using this regression equation the clearance could be estimated in reverse from the uptake coefficient calculated solely on the basis of the renoscintigraphic curves without blood sampling. The errors of the estimate are compatible with the requirement of a fast appraisal of renal function for purpose of clinical diagnosis. |
| | |
Authors:
|
M J Surma; J Liniecki; J Białobrzeski; E Młodkowska |
Related Documents
:
|
3014819 - Renal handling and effects of [3h]digoxin and interactions with quinidine in the avian ... 5338459 - Intrarenal distribution of blood flow in the transplanted dog kidney: effect of denerva... 1154799 - The disposition and metabolism of i.c.i. 58,834 (viloxazine) in humans. 22164449 - Microbubble generation and transmission of medtronic's affinity hardshell venous reserv... 833339 - The effect of indomethacin, 6-hydroxydopamine, saralasin, and hemorrhage on renal hemod... 3939089 - Differentiation of glomerular and non-glomerular haematurias on basis of the morphology... 1922919 - A quantitative study of the coincidence of blood vessels and a4 protein deposits in alz... 11008979 - Venous blood flow measurement by determination of change in venous hemoglobin saturation. 21448629 - Metals, nutrients and total suspended solids discharged during different flow condition... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Nuklearmedizin. Nuclear medicine Volume: 20 ISSN: 0029-5566 ISO Abbreviation: Nuklearmedizin Publication Date: 1981 Dec |
Date Detail:
|
Created Date: 1982-04-12 Completed Date: 1982-04-12 Revised Date: 2007-01-12 |
Medline Journal Info:
|
Nlm Unique ID: 7609387 Medline TA: Nuklearmedizin Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 274-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Computers* Humans Iodohippuric Acid / diagnostic use Online Systems Radioisotope Renography / methods* Renal Circulation* |
| Chemical | |
Reg. No./Substance:
|
147-58-0/Iodohippuric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Thyroid hormone concentrations in dialysate during hemodialysis in children.
Next Document: Determination of radiochemical purity and pharmacokinetic parameters of 99mTc-sulphur colloid and 99...